The Prognoses Factors That Influenced The Occurrence of Post-Endorectal Surgery Constipation of Pull Through at Dr. Sardjito Hospital

Ardean, Rochadi Residence of General Surgery Faculty of Medicine of UGM/Dr. Sardjito Hospital Yogyakarta Division of Surgery Faculty of Medicine of UGM/Dr. Sardjito Hospital Sub-Division of Pediatric Surgery Faculty of […]

NRG1 variant effects in patients with Hirschsprung disease

Gunadi, Nova Yuli Prasetyo Budi, Raman Sethi, Aditya Rifqi Fauzi, Alvin Santoso Kalim, Taufik Indrawan, Kristy Iskandar, Akhmad Makhmudi, Indra Adrianto and Lai Poh San Background: Hirschsprung disease (HSCR) is […]

Liver transplant score for prediction of biliary atresia patients’ survival following Kasai procedure

Abstract Objectives: Recently, a scoring system has been developed to predict which patients with biliary atresia (BA) who underwent a Kasai procedure should be considered for liver transplant. Here, we […]

Combined genetic effects of RET and NRG1 susceptibility variants on multifactorial Hirschsprung disease in Indonesia

Abstract Background Specific genetic variants at RET (rs2435357) and NRG1 (rs7835688, rs16879552) are associated with Hirschsprung disease (HSCR) in Indonesia. This study aimed to investigate the additional effect of RET […]

The impact of down-regulated SK3 expressions on Hirschsprung disease

Abstract BACKGROUND: Some Hirschsprung’s disease (HSCR) patients showed persistent bowel symptoms following an appropriately performed pull-through procedure. The mechanism is presumed to be down-regulated small-conductance calcium-activated potassium channel 3 (SK3) […]

Functional outcomes in Hirschsprung disease patients after transabdominal Soave and Duhamel procedures

Background Several pull-through procedures have been described for Hirschsprung disease (HSCR) with varying functional outcomes. The voluntary bowel movement (VBM) and the absence of soiling or constipation after pull-through remain […]

Outcomes in patients with Hirschsprung disease following definitive surgery

Objective Several pull-through procedures have been described for Hirschsprung disease (HSCR) with varying outcomes. We aimed to describe the outcomes in HSCR patients < 18 year of age who underwent surgical […]

Comparison of Hirschsprung-associated enterocolitis following Soave and Duhamel procedures

Abstract BACKGROUND: Hirschsprung-associated enterocolitis (HAEC) represents the primary cause of high morbidity and mortality in Hirschsprung disease (HSCR) patients. The most common surgical methods for HSCR are the Soave and […]

AB087. Synergistic genetic effects of RET and NRG1 susceptibility variants in Hirschsprung disease

Abstract Background Hirschsprung disease (HSCR) is a complex genetic disorder, which characterized by absence of ganglion cells along variable lengths of the intestines in neonates, with the RET and NRG1 […]

The utility of the hematoxylin and eosin staining in patients with suspected Hirschsprung disease

Background While immunohistochemistry (IHC) methods have been widely conducted for the diagnosis of Hirschsprung disease (HSCR) in developed countries, there are very few studies on their use in developing countries […]